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CJC-1295 with DAC
Lyophilized · Compounded · GMP Certified
+ $19.99 shipping sales tax by state, shown at checkout
Strength
Quantity
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Third-party lab tested HPLC-tested · CoA included with your order
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Ships in 1 business day Order by 1 PM EST
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Discreet packaging Cold-pack available
What is CJC-1295 with DAC?
CJC-1295 with DAC is the long-acting version of the GHRH analog CJC-1295. The added “drug-affinity complex” (DAC) lets it bind to albumin in the blood, stretching its action from minutes to days — a sustained elevation of growth hormone and IGF-1.
How CJC-1295 (DAC) works
Like all GHRH analogs, CJC-1295 binds the GHRH receptor on the pituitary and stimulates the body’s own growth hormone. The DAC version adds a group that covalently binds circulating albumin, protecting the peptide from breakdown and giving a half-life of roughly 6–8 days. Rather than a brief pulse (as with the No-DAC form), it produces a sustained, multi-day rise in GH and IGF-1.
What the research shows
- Prolonged GH/IGF-1 (Teichman et al., 2006). A single dose raised GH 2–10× and IGF-1 1.5–3× for up to ~6–11 days in healthy adults, with an estimated half-life of ~6–8 days.
- Pulsatility preserved (Ionescu & Frohman, 2006). Continuous CJC-1295 stimulation raised GH while preserving the natural pulsatile rhythm.
- Restored growth in models (Alba et al., 2006). Once-daily CJC-1295 normalised growth and raised IGF-1 in GHRH-deficient mice.
Candour: human data are limited to these pharmacokinetic studies; long-term safety and efficacy outcomes are not established. Use belongs under a physician’s guidance.
Molecular specification
| Type | GHRH analog · modified GRF(1-29) with DAC |
| Sequence | 30-aa GRF(1-29) analog + drug-affinity complex |
| Molecular formula | C165H269N47O46 |
| Molecular weight | ≈3647.2 g/mol |
| Half-life | ~6–8 days (albumin-binding DAC) |
| CAS number | 446262-90-4 |
Quality and sourcing
Every batch of Azzurri Wellness CJC-1295 with DAC is compounded through a Registered 503B outsourcing facility under GMP-compliant processes, HPLC-tested for purity and potency, and third-party lab verified. Shipped cold-pack when needed to protect stability.
References
- Teichman SL, et al. Prolonged stimulation of GH and IGF-I secretion by CJC-1295, a long-acting analog of GHRH, in healthy adults. J Clin Endocrinol Metab. 2006;91(3):799–805. PubMed
- Ionescu M, Frohman LA. Pulsatile secretion of GH persists during continuous stimulation by CJC-1295. J Clin Endocrinol Metab. 2006;91(12):4792–4797. PubMed
- Alba M, et al. Once-daily CJC-1295 normalizes growth in the GHRH knockout mouse. Am J Physiol Endocrinol Metab. 2006;291(6):E1290–E1294. PubMed
Compiled by the Azzurri Wellness Research Team and checked against the cited literature. Educational only — not medical advice.
What CJC-1295 W/ DAC
is studied for
Here’s a plain-English look at the areas researchers focus on with CJC-1295 with DAC — context to discuss with your physician, not medical advice.
Long-acting GH
Albumin binding gives a ~6–8 day half-life and sustained GH release.
IGF-1 elevation
Raises IGF-1 for days after a single dose.
DAC technology
The drug-affinity complex is what extends its action.
Fewer doses
Its long half-life means less frequent dosing than the No-DAC form.
GHRH analog
Stimulates the body’s own growth hormone via the GHRH receptor.
Frequently asked questions
What does DAC mean in CJC-1295 with DAC?
DAC stands for Drug Affinity Complex, a chemical group that lets the peptide bind albumin in the blood. That stretches its half-life from about 30 minutes (for CJC-1295 without DAC, also called mod GRF 1-29) to roughly 6 to 8 days.
What is the difference between CJC-1295 with and without DAC?
Both are modified versions of GHRH (1-29) that prompt the pituitary to release growth hormone. Without DAC, the peptide gives a short pulse; with DAC, it keeps growth hormone signalling raised for days.
What do the studies show for CJC-1295 with DAC?
In a 2006 study in healthy adults, a single injection raised growth hormone levels 2- to 10-fold for six days or more, and IGF-1 levels 1.5- to 3-fold for up to 11 days.
How much CJC-1295 with DAC should I take?
Dosing, frequency and injection site are set by the prescribing physician for each person, so we don’t give dosing advice. If you need help with the mixing math for a dose your physician has set, our free peptide reconstitution calculator works it out for any vial size.
Open the reconstitution calculator →Where can I buy CJC-1295 with DAC?
You can buy CJC-1295 with DAC online here at Azzurri Wellness and it ships fast and discreetly across the USA. Every vial is prepared by a Registered 503B outsourcing facility under GMP-compliant conditions, third-party lab tested for identity and purity, and shipped with the Certificate of Analysis for your batch.
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